منابع مشابه
Intrinsic fluorescence studies on saccharide binding to Artocarpus integrifolia lectin.
The combining region of Artocarpus integrifolia lectin has been studied by using the ligand-induced changes in the fluorescence of the lectin. The saccharide binding properties of the lectin show that C-1, C-2, C-4, and C-6 hydroxyl groups of D-galactose are important loci for sugar binding. The alpha-anomer of galactose binds more strongly than its beta-counterpart. Inversion in the configurat...
متن کاملFurther characterization and immunochemical studies on the carbohydrate specificity of jackfruit (Artocarpus integrifolia) lectin.
The lectin from jackfruit (Artocarpus integrifolia) seeds has been purified by Rivanol (6,9-diamino-2-ethoxyacridine lactate) treatment. The specific activity, molecular weights of parent lectin and its subunit, its glycoprotein nature, and hemagglutination-inhibition assays suggest that this preparation is identical to that obtained by affinity chromatography on melibiose-agarose adsorbent (Ah...
متن کاملBinding of porphyrins by the tumor-specific lectin, jacalin [Jack fruit (Artocarpus integrifolia) agglutinin].
Jacalin (Artocarpus integrifolia agglutinin) specifically recognizes the tumor-associated T-antigenic disaccharide structure, Gal beta13GalNAc. Porphyrins and their derivatives are currently used as photosensitizers in photodynamic therapy to treat malignant tumors. In this study, the interaction of several free base porphyrins and their metal derivatives with jacalin is investigated by absorpt...
متن کاملFrutapin, a lectin from Artocarpus incisa (breadfruit): cloning, expression and molecular insights
Artocarpus incisa (breadfruit) seeds contain three different lectins (Frutalin, Frutapin (FTP) and Frutackin) with distinct carbohydrate specificities. The most abundant lectin is Frutalin, an α-D-galactose-specific carbohydrate-binding glycoprotein with antitumour properties and potential for tumour biomarker discovery as already reported. FTP is the second most abundant, but proved difficult ...
متن کاملChemical Constituents of Artocarpus altilis and Artocarpus odoratissimus
Chemical investigation of the dichloromethane extract of the leaves of Artocarpus altilis yielded βsitosterol (1), unsaturated triglycerides (2), squalene (3), polyprenol (4), lutein (5) and unsaturated fatty acids. The structures of 1-5 were identified by comparison of their 1 H and/or 13 C NMR data with those reported in the literature. Chemical investigation of the dichloromethane extract of...
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ژورنال
عنوان ژورنال: European Journal of Biochemistry
سال: 2002
ISSN: 0014-2956
DOI: 10.1046/j.1432-1033.2002.02789.x